Juvenile Localized Scleroderma with Hyaline Deposits in the Renal Arteriole
نویسندگان
چکیده
منابع مشابه
Juvenile localized scleroderma: review of 44 patients
Results 70.5% of patients were females. CM (34.1%) and LM (34.1%) were the most frequently subtypes. Mean age at first symptoms was 7.7 years (Figure 1). Medium time between first signs/symptoms and diagnosis was 15.42 months. One patient with CM head-neck lesions had Parry-Romberg disease with neurological involvement. 50% of patients with head-neck LM had “coup de sabre” subtype, 25% of that ...
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Introduction Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood. Localized scleroderma also known as morphea is an inflammatory, fibrosing skin disorder that leads to sclerosis of the dermis and eventually of the underlying tissues. The prevalence is estimated at around 1-9/100,000 with the onset before 10 years of age in 2% of patients. The associatio...
متن کاملLong-term methotrexate efficacy in juvenile localized scleroderma
Methods We prospectively followed a cohort of patients with JLS who were enrolled in a double-blind, randomized controlled trial. Oral MTX was used at a dose of 15 mg/m once a week (max 20 mg) for at lest 24 months; prednisone (1 mg/Kg/day, max 50 mg), in a single morning dose for 3 months was added. A target lesion was evaluated clinically, with infrared thermography and using a computerized s...
متن کاملEsophageal involvement in juvenile localized scleroderma: a pilot study.
OBJECTIVES To evaluate the esophageal involvement in patients with juvenile localized scleroderma (JLS). METHODS A cohort of patients with JLS underwent esophageal stationary manometry to evaluate esophageal motility and lower esophageal sphincter (LES) function, distal esophagus 24-hour pH-monitoring to detect gastroesophageal reflux (GER) and upper gastrointestinal (GI) endoscopy to evaluat...
متن کاملEfficacy and safety of methotrexate treatment of juvenile localized scleroderma
Retrospective study of 59 chlidren with JLS from 3 to 17 y (M = 10.3) treated with MTX was performed. Group 1 (n = 18) – received prednisone 0.5 mg\kg for 6 weeks, taped to 0.1 mg\kg for 12 months + MTX 10 mg\body sq. weekly for 13.7 mo. Group 2 (n = 41) -MTX the same doses and duration. The efficacy was measured in 6 & 12 months using skin score, activity and sclerosis indexes (IA, IS) (1 – 3 ...
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ژورنال
عنوان ژورنال: Case Reports in Dermatology
سال: 2018
ISSN: 1662-6567
DOI: 10.1159/000488901